Evaluation of Bakuchiol Derivatives as Potential Anticancer Agents.
Bakuchiol derivatives were shown to be effective at down-regulating various cellular expression pathways and downstream proteins that have been implicated with cancerous activity. the research was conducted in a specific, and research use only cell line.
Why that is important:
Bakuchiol has to potential to help increase the general health of cells through the observed modulation of various cellular pathways. the journal article does not directly relate to the skin, but it does provide insight as there are many commonalities between cells in various organs.
WU CZ, LIU DC, GUO X, DAI Y, MA T, LI HM, HUO Q. SYNTHESIS AND EVALUATION OF BAKUCHIOL DERIVATIVES AS POTENTIAL ANTICANCER AGENTS. MOLECULES. 2018 FEB 26;23(3):515. DOI: 10.3390/MOLECULES23030515. PMID: 29495380; PMCID: PMC6017251.